Helical Repeat Protein mRSiC is Required for rRNA Fragment Accumulation in T. gondii Mitochondria
Nikiforos Drakoulis, Sascha Maschmann, Zala Gluhic, Alea Boujianna Blum, Arne Hillebrand, Alexandra Possling, Victor Martin Quintana Flores, Ross F. Waller, Giel G. van Dooren, Christian Schmitz‐Linneweber, Sabrina Tetzlaff
The paper identifies mRSiC, an HPR protein in Toxoplasma gondii, as essential for stabilizing mitochondrial sRNAs and maintaining rRNA fragments, respiratory chain function, and parasite proliferation.
bioRxiv · Feb 12, 2026 · PreprintMolecular Biology