Ross F. Waller

This paper identifies a cell cycle checkpoint in Plasmodium falciparum in response to DNA damage, suggesting checkpoint kinase activity despite lacking clear homologues, and proposes checkpoint inhibitors as potential synergists with artemisinin.

The paper shows that TgmRHel processes coxI mRNA precursors generated from a recombining mitochondrial genome into a mature transcript, essential for parasite survival.

This study maps the spatial proteome of Plasmodium falciparum schizonts, identifying 24 cellular niches and classifying 1646 proteins, while revealing evolutionary patterns in parasite organelles.

The paper identifies mRSiC, an HPR protein in Toxoplasma gondii, as essential for stabilizing mitochondrial sRNAs and maintaining rRNA fragments, respiratory chain function, and parasite proliferation.

This study identifies two Plasmodium virulence factors involved in lipid metabolism and disease progression by analyzing their function in vivo.

This paper introduces a semi-supervised Bayesian method to integrate spatial proteomics data with other omic datasets to improve protein subcellular localization inference.

This study shows that dinoflagellates can acquire and utilize haptophyte-derived plastids, demonstrating that complex plastids can be transferred between hosts.

This study identifies and characterizes the DNA damage checkpoint kinases ATM and ATR in Toxoplasma gondii, revealing their unique roles in regulating replication and response to DNA damage.

This study identifies and characterizes the Toxoplasma gondii ABCB7 homolog, showing its essential role in cytosolic iron-sulfur cluster biogenesis and protein translation.

This study uses single-cell transcriptomics to map the early placental response to three pathogens in first-trimester human placenta, identifying coordinated inflammatory responses and pathogen-specific effects.

The paper sequences four Perkinsus mitochondrial genomes, identifies conserved frameshifts in all genes, and proposes a decoding mechanism involving unused codons.

The paper identifies and validates a comprehensive list of mitochondrial proteins in Plasmodium falciparum using Bayesian statistics and experimental confirmation.

This paper develops genetic tools for Perkinsus marinus, enabling efficient transgene expression and selection, and identifies genomic integration mechanisms.

The paper demonstrates stable genetic transformation of dinoflagellate chloroplasts using a plasmid-like fragmented chloroplast genome, showing long-term expression and maintenance of introduced genes.

This study identifies and characterizes PPR1, an essential apicoplast-targeted PPR protein in Plasmodium that binds specific RNA sequences and protects transcripts from degradation.