Giel G. van Dooren

This study shows doxycycline inhibits apicoplast and mitochondrial translation in Plasmodium falciparum and Toxoplasma gondii, reducing protein abundance and mitochondrial complex IV activity.

The paper shows that TgmRHel processes coxI mRNA precursors generated from a recombining mitochondrial genome into a mature transcript, essential for parasite survival.

This study identifies two copper transporters in Toxoplasma gondii and shows their roles in parasite metabolism and persistence.

The paper identifies mRSiC, an HPR protein in Toxoplasma gondii, as essential for stabilizing mitochondrial sRNAs and maintaining rRNA fragments, respiratory chain function, and parasite proliferation.

This paper identifies a proton transfer mechanism in the malaria parasite lactate/H+ symporter, showing it functions as a transporter without conformational changes and can switch between transporter and channel modes.

The paper identifies ZFT as the primary iron and zinc transporter in Toxoplasma gondii, showing its essential role in parasite survival and metal homeostasis.