Comparative toxicity of menthol- and tobacco-flavored electronic cigarette constituents causing inflammation, epithelial barrier dysfunction, and nicotinic acetylcholine receptor modulation in the absence of nicotine.
Vidhi S. Pandya, Arni Bhatnagar, Kirby J. Beck, Thivanka Muthumalage
This study investigates the toxic effects of menthol- and tobacco-flavored e-cigarette constituents on lung epithelial cells, showing inflammation, barrier dysfunction, and nicotinic acetylcholine receptor modulation without nicotine.
bioRxiv · Jun 30, 2025 · PreprintPharmacology & Toxicology