A Fast and efficient strategy for the NMR assignment of Fab methyl groups
Faustine Henot, Béatrice Vibert, Arthur Giraud, Sarra Dbira, Lionel Imbert, Adrien Favier, Peter Güntert, Séverine Clavier, Elodie Crublet, Camille Doyen, Jérôme Boisbouvier, Oriane Frances
This paper introduces a strategy to rapidly assign methyl groups in IgG1 Fab fragments using sequence identities and partial assignments, reducing the need for deuterated samples.
Journal of Biomolecular NMR · Feb 17, 2026Peer-reviewedBiochemistry