Toward Site-Specific Characterization of Structural Perturbations on Glycosylated Fc Using NMR at Natural Abundance
Béatrice Vibert, Sarah Nguyen, Faustine Henot, Camille Doyen, Oscar Hernandez‐Alba, Sarah Cianférani, Séverine Clavier, Oriane Frances, Jérôme Boisbouvier
This paper presents a methyl group assignment for the Fc fragment of an IgG1 antibody using NMR, enabling structural analysis of glycosylated Fc without isotopic labelling.
Journal of Biomolecular NMR · Feb 17, 2026Peer-reviewedBiochemistry