Arundhaty Pal

Association of miR-181a-5p with Lantana camara leaf extract-mediated inhibition of proliferation, survival, and migration in luminal A-type MCF-7 cells and triple-negative type MDA-MB-231 cells

This study shows that Lantana camara leaf extract increases miR-181a-5p expression, which reduces proliferation, survival, and migration of breast cancer cells by targeting BCL-2, MCL-1, and CDKN3.

Lantana camara leaf extract-mediated suppression of DNA methyltransferase 1 promotes G0/G1 cell cycle arrest and apoptosis, and impedes migration in MDA-MB-231 triple-negative breast cancer cells

This study shows that Lantana camara leaf extract suppresses DNMT1, leading to tumor suppressor gene reactivation, G0/G1 arrest, apoptosis, and reduced migration in TNBC cells.