Phage-encoded cationic antimicrobial peptide used for outer membrane disruption in lysis
Ashley Holt, Jesse Cahill, Jolene Ramsey, Chandler O’Leary, Russell Moreland, Cody Martin, Don Thushara Galbadage, Riti Sharan, Preeti Sule, Kelsey Bettridge, Jie Xiao, Jeffrey Cirillo, Ryland Young
This study identifies a phage-encoded cationic antimicrobial peptide, Gp28, that disrupts bacterial outer membranes during lysis, functioning similarly to human antimicrobial peptides like LL-37.
bioRxiv · Jan 8, 2019 · PreprintMicrobiology