GeneticsNature CommunicationsPeer-reviewed
Higher-order epistasis shapes natural variation in germ stem cell niche activity
Sarah R. Fausett, Asma Sandjak, Bénédicte Billard, Christian Braendle
The paper identifies a 148 bp deletion in the lag-2 promoter as a causal variant for variation in germ stem cell niche activity in C. elegans, but shows that its effects are modulated by higher-order epistasis.
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