Predicting the Purity of Multispecific Antibodies From Sequence Using Machine Learning: Methods and Applications
Aviva Mazurek, Athena Davis, Stephen R. Comeau, Kenny Tsang, Javier Rivera, Zhong-Fu Huang, John Holt, Sandeep Kumar, Srinath Kasturirangan
This paper uses machine learning to predict antibody purity from sequence and format data, showing it can effectively estimate monomer percentage in multispecific antibodies.
bioRxiv · Dec 5, 2023 · PreprintMolecular Biology