Author

Stephen R. Comeau

Boehringer Ingelheim (United States)ORCID 0000-0003-4281-2026Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Assay:protein sequence· 2 Approach:benchmark study· 1 Approach:deep learning· 1 Approach:machine learning (classical)· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Adithya PolasaiD· 2 shared Bartosz JanusziD· 2 shared Dawid ChomicziD· 2 shared Konrad KrawczykiD· 2 shared Kyle MartiniD· 2 shared Paweł DudziciD· 2 shared Sonia WrobeliD· 2 shared Steven J. Darnell· 2 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBioinformatics

Adithya PolasaORCID

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3 papers

Recent·Most cited

BioinformaticsBioinformatics AdvancesPeer-reviewedJan 1, 2026

Benchmarking antigen-aware inverse folding methods for antibody design.

Bartosz Janusz, Dawid Chomicz, Sonia Wrobel…·Konrad Krawczyk

This study benchmarks inverse folding methods for antibody design to assess their effectiveness in predicting binder sequences given a structure.

2 citations

protein structurebenchmark study

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BioinformaticsbioRxivPreprintApr 29, 2025

nanoFOLD : sequence design of nanobodies via inverse folding

Dawid Chomicz, Bartosz Janusz, Sonia Wrobel…·Konrad Krawczyk

The paper introduces nanoFOLD, an inverse folding method for designing nanobodies, and applies it to binder enrichment and novel design.

DOI 10.1101/2025.04.29.651236

protein sequencedeep learning

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Molecular BiologybioRxivPreprintDec 5, 2023

Predicting the Purity of Multispecific Antibodies From Sequence Using Machine Learning: Methods and Applications

Aviva Mazurek, Athena Davis, Stephen R. Comeau…·Srinath Kasturirangan

This paper uses machine learning to predict antibody purity from sequence and format data, showing it can effectively estimate monomer percentage in multispecific antibodies.

1 citation

protein sequencemachine learning (classical)

𝕏 PostBluesky