Expanded stoichiometric model of chondrocyte metabolism: response to cyclical shear and compressive loading
Aubrey Kimmel, Adrienne D. Arnold, Ayten E. Erdogan, Ronak Kommineni, Erik P. Myers, Bree Cummins, Ross P. Carlson, Ronald K. June
This study develops a stoichiometric model of chondrocyte metabolism to examine how cyclical shear and compressive loading affect matrix protein synthesis, revealing sex-dependent differences and nitrogen limitations.
Journal of Biomechanical Engineering · Aug 5, 2026Peer-reviewedBioengineering