Chemically diverse antagonists inhibit human TRPV1 through ligand-specific interaction networks
Kyle Eric Lopez, Audrey D. Paduda, Matthew J. Derrick, Wade D. Van Horn
The paper identifies how diverse TRPV1 antagonists interact with the receptor through different binding modes and highlights conserved inhibited states.
bioRxiv · Oct 7, 2026 · PreprintBiophysics