An evolutionary strategy for highly efficient secretion of multidomain Staphylococcal protein A: N- to C-terminal stability gradient
Andrew Hagarman, William R. Franch, Aulane Mpouli, Bruce Randall Donald, Terrence G. Oas
The paper measures folding thermodynamics of SpA domains and identifies a stability gradient that facilitates efficient secretion.
bioRxiv · Oct 28, 2026 · PreprintBiophysics