Feng Yu

AlphaSAXS uses SAXS data to guide AI in reconstructing accurate protein conformations, improving upon sequence-only models by incorporating experimental constraints.

The paper evaluates computational methods for predicting interdomain pose distributions in D-L-D proteins using NMR and SAXS data, finding none accurately match experimental results.

This study examines how four Arabidopsis LEA proteins respond structurally and functionally to environmental changes, revealing distinct protective mechanisms under desiccation.

This study shows LEA_4 motifs protect an enzyme during desiccation, with enhanced protection when combined with synergistic cosolutes.

The paper investigates how structural ensembles of disordered activation domains correlate with transcriptional activity through mutational analysis of HIF-1 and CITED2.