Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease
Joshua Moss, Judith Magenheim, Daniel Neiman, Hai Zemmour, Netanel Loyfer, Amit Korach, Yaacov Samet, Myriam Maoz, Henrik Druid, Peter Arner, Keng‐Yeh Fu, Endre Kiss, Kirsty L. Spalding, Giora Landesberg, Aviad Zick, , Yuval Dor
The paper develops a method to determine the tissue origins of circulating cell-free DNA using a methylation atlas and validates it in healthy and disease states.
Nature Communications · Nov 23, 2018Peer-reviewedMolecular Biology