A prophage-encoded anti-phage defense system that prevents phage DNA packaging by targeting the terminase complex
Gil Azulay, Nadejda Sigal, Keren Tzohar Rabinovich, Dan Koenigsfeld, Olga Stadnyuk, Avijit Das, Polina Lisitzin, Einat Biderman, Ilya Borovok, Anat A. Herskovits
The paper identifies a prophage-encoded anti-phage defense system in Listeria monocytogenes that prevents phage DNA packaging by targeting the terminase complex, without halting the lytic cycle.
bioRxiv · Feb 27, 2025 · PreprintMicrobiology