Lupeol, a bioactive compound of tamarind, functions as a potent inhibitor of hepatitis C virus (HCV) entry through disruption of the E2-CD81 interaction.
Maitri Singh, Chayan Bhattacharjee, Avik Bardhan, Aparna Mukhopadhyay
This study identifies lupeol from tamarind as a potent inhibitor of HCV entry by disrupting the E2-CD81 interaction, validated through experimental and computational methods.
bioRxiv · Jul 26, 2026 · PreprintMicrobiology