Choice-selective sequences dominate in cortical relative to thalamic inputs to the nucleus accumbens, providing a potential substrate for credit assignment
Nathan F. Parker, Avinash Baidya, Julia Cox, Laura M. Haetzel, Anna Zhukovskaya, Malavika Murugan, Ben Engelhard, Mark S. Goldman, Ilana B. Witten
The paper compares cortical and thalamic inputs to the nucleus accumbens in mice during a reinforcement learning task, finding that cortical inputs represent actions and choices while thalamic inputs represent cues, with cortical sequences supporting reinforcement learning.
bioRxiv · Sep 2, 2021 · PreprintNeuroscience