Hematopoietic proliferation is orchestrated by the sequential and lineage-specific activation of Cyclin D, Cyclin E and CDKN sub-modules within the G1/S network
Andrea Hänel, Aya Abdelsalam, Sylvain Tollis
The paper uses single cell transcriptomics and mathematical modeling to show how cyclin D, cyclin E, and CDKN sub-modules in the G1/S network drive distinct proliferation trajectories in hematopoietic cells.
bioRxiv · May 15, 2025 · PreprintSystems Biology