Author

Ayako Hirota

Tokai University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

Asuka MiyamotoiD· 1 shared Atsushi YasudaiD· 1 shared Banri TsudaiD· 1 shared Daiki Kirigaya· 1 shared Hirofumi Kashiwagi· 1 shared Hitoshi IshimotoiD· 1 shared Jerzy K. KulskiiD· 1 shared Mao Suzuki-Ohno· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Asuka MiyamotoORCID

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1 paper

Recent·Most cited

Human Interleukin-4-Dependent Facilitation of Human IgG Production in PBL-NOG-hIL-4-Tg mice

Yoshie Kametani, Shino Ohshima, Ryoji Ito, Yusuke Ohno, Soga Yamada, Yuki Hoshino, Asuka Miyamoto, Mao Suzuki-Ohno, Nagi Katano, Banri Tsuda, Mariko Miyazawa, Hirofumi Kashiwagi, Daiki Kirigaya, Tomoka Shimizu, Mika Kojima, , Takashi Shiina

This study shows that NOG-hIL-4-Tg mice support human IgG production through IL-4-dependent B cell maintenance and class switching, with varying subclass responses and tertiary lymphoid structures.

Frontiers in Immunology · Nov 26, 2025Peer-reviewedImmunology