High frequency DBS-like optogenetic stimulation of nucleus accumbens dopamine D2 receptor-containing neurons attenuates cocaine reinstatement in male rats
Sarah E. Swinford-Jackson, Phillip J. Huffman, Melissa C. Knouse, Arthur S. Thomas, Matthew T. Rich, Sharvari Mankame, Samantha J. Worobey, Mateo Sarmiento, Ayanna Coleman, Robert Christopher Pierce
The paper tests if optogenetic stimulation of specific dopamine receptor neurons in the nucleus accumbens reduces cocaine seeking in male rats, finding it reduces seeking when targeting D2DR neurons.
Neuropsychopharmacology · Nov 29, 2022Peer-reviewedNeuroscience