Aberrant expression of collagen type X in solid tumor stroma is associated with EMT, immunosuppressive and pro-metastatic pathways, bone marrow stromal cell signatures, and poor survival prognosis
Elliot H. H. Youth, Aryana Famili-Youth, Dongfang Yang, Ayesha Siddique, Elizabeth Yiru Wu, Wenguang Liu, Murray B. Resnick, Qian Chen, Alexander S. Brodsky
This study identifies COL10A1-associated gene networks in breast and pancreatic cancer that link to EMT, immunosuppression, metastasis, and poor prognosis.
BMC Cancer · Feb 12, 2025Peer-reviewedCancer Biology