Author

Alexander S. Brodsky

Brown UniversityORCID 0000-0001-7357-5153Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Andrea SchmidtiD· 1 shared Aryana Famili-YouthiD· 1 shared Ayesha Siddique· 1 shared Ayush BharatiiD· 1 shared Bin WuiD· 1 shared Bogdan I. FedelesiD· 1 shared Choi‐Fong ChoiD· 1 shared Dongfang Yang· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Andrea SchmidtORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Modulation of blood-tumor barrier transcriptional programs improves intra-tumoral drug delivery and potentiates chemotherapy in GBM

Jorge L. Jimenez-Macias, Philippa C. Vaughn-Beaucaire, Ayush Bharati, Zheyun Xu, Megan E. Forrest, Jason S. Hong, Michael Sun, Andrea Schmidt, Jasmine Clark, William M. Hawkins, Noe B. Mercado, Jacqueline Real, Kelsey E. Huntington, Mykola I. Zdioruk, Michal Oskar Nowicki, , Sean Edward Lawler

This study identifies a 12-gene BTB signature, shows CDH5 as a core component, and demonstrates that BIA disrupts the BTB to enhance chemotherapy delivery and efficacy in GBM.

Science Advances · Feb 26, 2025Peer-reviewedCancer Biology

Aberrant expression of collagen type X in solid tumor stroma is associated with EMT, immunosuppressive and pro-metastatic pathways, bone marrow stromal cell signatures, and poor survival prognosis

Elliot H. H. Youth, Aryana Famili-Youth, Dongfang Yang, Ayesha Siddique, Elizabeth Yiru Wu, Wenguang Liu, Murray B. Resnick, Qian Chen, Alexander S. Brodsky

This study identifies COL10A1-associated gene networks in breast and pancreatic cancer that link to EMT, immunosuppression, metastasis, and poor prognosis.

BMC Cancer · Feb 12, 2025Peer-reviewedCancer Biology