Red blood cell-tumour cell interactions promote tumour cell progression
Thais Pereira‐Veiga, Celso Yáñez-Gómez, Aleksi Pekkarinen, Carmen Abuín, Christine Blechner, Miriam González-Conde, Christian Meß, Sabine Vidal‐y‐Sy, Ayham Moustafa, Bente Siebels, Ana Belén Dávila-Ibáñez, Pablo Cabezas‐Sainz, Maider Santos, Laura Sánchez, Joao Gorgulho, , Clotilde Costa
This study shows that red blood cells from cancer patients enhance tumour cell invasiveness and metastatic potential through gene and protein changes, suggesting PAK4 as a therapeutic target.
Journal of Experimental & Clinical Cancer Research · Apr 29, 2025Peer-reviewedCancer Biology