Computational Analysis of Silent Mutation Effects on SARS-CoV-2 RNA-Host RNA-Binding Protein Interactome
Adebayo J. Bello, Onyeka S. Chukwudozie, Olajumoke Bisola Oladapo, Ayomide O. Omotuyi, Nnamdi A. Nzoniwu, Oluwafemi Daniel Amusa, Bodunrin Ottu, Uche Valentine Okeke, Abeebat O. Adewole, Ololade O. Akinnusi, Ayomikun Emmanuel Kade, J.B. Minari, Joy Okpuzor, Onikepe A. Folarin, Mujeeb Olushola Shittu
The paper investigates how silent mutations in SARS-CoV-2 affect RNA-binding protein interactions by generating synthetic variants and analyzing RBP binding patterns.
bioRxiv · Sep 22, 2025 · PreprintBioinformatics