Ayomikun Emmanuel Kade

Tetrasodium EDTA disrupts Pseudomonas aeruginosa membrane integrity, shows suppressed resistance evolution and reduced cytotoxicity compared to meropenem

This study shows that tEDTA disrupts Pseudomonas aeruginosa membranes, suppresses resistance evolution, and has lower cytotoxicity than meropenem.

Low concentrations of tetrasodium EDTA cause significant killing of biofilm-associated P. aeruginosa in high validity models of chronic wound and CF lung infections but not in a model of endotracheal tube colonisation

This study evaluates the efficacy of tetrasodium EDTA against P. aeruginosa biofilms in different infection models, finding it effective in chronic wound and CF lung infections but not in endotracheal tube colonization.

Does media matter? Growth environment influence antimicrobial tolerance and expression of virulence and transmembrane ion transport-associated genes in MRSA

This study shows that growth media affects gene expression, virulence, and antibiotic tolerance in MRSA, highlighting the need for physiologically relevant media in antimicrobial testing.

Computational Analysis of Silent Mutation Effects on SARS-CoV-2 RNA-Host RNA-Binding Protein Interactome

The paper investigates how silent mutations in SARS-CoV-2 affect RNA-binding protein interactions by generating synthetic variants and analyzing RBP binding patterns.