Early identification of cooperative fragments for protein-protein interaction stabilization
P. J. de Vink, P. J. Cossar, B. A. Somsen, C. O. Ottmann, L. Brunsveld
The paper identifies cooperative fragments that stabilize protein-protein interactions using STD NMR and validates their effects through mutagenesis and crystallography.
bioRxiv · Feb 23, 2022 · PreprintBiochemistry