Optogenetic control of a GEF of RhoA uncovers a signaling switch from retraction to protrusion
J. de Seze, M. Bongaerts, B. Boulevard, M. Coppey
The paper uses optogenetics to control RhoA GEF localization, showing a single protein can induce retraction or protrusion based on its concentration, revealing a signaling switch mechanism.
eLife · May 27, 2025Peer-reviewedCell Biology