Tissue-bound hyaluronan molecular weight as a regulator of dendritic cell immune potency
B. C. Quartey, J. Sapudom, M. ElGindi, A. Alatoom, J. Teo
This study investigates how different molecular weights of tissue-bound hyaluronan affect dendritic cell functions, finding that low MW HA enhances immature DC differentiation and antigen uptake, while medium and high MW HA increase cytokine secretion in matured DCs.
bioRxiv · Jun 6, 2023Bioengineering