Pseudomonas aeruginosa cytochrome P450 CYP168A1 is a fatty acid hydroxylase that metabolizes arachidonic acid to the vasodilator 19-HETE
B. C. Tooker, S. E. Kandel, H. M. Work, J. N. Lampe
This study identifies Pseudomonas aeruginosa CYP168A1 as a fatty acid hydroxylase that converts arachidonic acid to 19-HETE, a vasoconstrictor potentially aiding pathogen colonization.
bioRxiv · Oct 19, 2021Biochemistry