Adaptation of a fluoroquinolone-sensitive Shigella sonnei to norfloxacin exposure
B. C. Wong, S. K. K. Law, M. Z. H. Md Zoqratt, Q. Ayub, H. S. Tan
This study shows that a norfloxacin-sensitive Shigella sonnei strain responds to sub-lethal norfloxacin by downregulating ribosomal proteins and altering ppGpp levels, which affects its tolerance to the antibiotic.
bioRxiv · Dec 8, 2020 · PreprintMicrobiology