Revisiting the trafficking of insulin and its receptor in rat liver: in vivo and cell-free studies
K. Tahiri, F. Fouque, M.-C. Postel-Vinay, B. Desbuquois
This study investigates insulin and receptor trafficking in rat liver using in vivo and cell-free methods, finding that insulin is degraded in endosomes while the receptor is recycled without requiring new protein synthesis.
bioRxiv · Sep 7, 2023 · PreprintCell Biology