Redefining the specificity of phosphoinositide-binding by human PH domain-containing proteins
N. Singh, A. Reyes-Ordonez, M. A. Compagnone, J. F. Moreno Castillo, B. J. Leslie, T. Ha, J. Chen
The paper identifies 54% of human PH domain-containing proteins as having PIP binding affinity, using single-molecule pulldown assays and a recursive-learning algorithm.
bioRxiv · Jun 20, 2020Biochemistry