The proteostasis interactomes of trafficking-deficient KV11.1 variants associated with Long QT Syndrome and pharmacological chaperone rescue
C. L. Egly, T. Q. Do, E. F. McDonald, L. Barny, L. Plate, B. Knollmann
The paper identifies proteostasis interactomes of trafficking-deficient KV11.1 variants and shows pharmacological chaperone rescue of proteostasis network alterations in LQTS-associated variants.
bioRxiv · Jan 31, 2024 · PreprintBiochemistry