An Omic and Multidimensional Spatial Atlas from Serial Biopsies of an Evolving Metastatic Breast Cancer
B. E. Johnson, A. L. Creason, J. M. Stommel, J. M. Keck, S. Parmar, C. B. Betts, A. Blucher, C. Boniface, E. Bucher, E. A. Burlingame, T. Camp, K. Chin, J. Eng, J. Estabrook, H. S. Feiler, , J. W. Gray
This paper presents an OMS Atlas from serial biopsies of a metastatic breast cancer patient, linking clinical data to multi-omic and spatial profiles to study therapy-associated heterogeneity and resistance mechanisms.
bioRxiv · Dec 3, 2020Cancer Biology