Author

C. Boniface

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 4

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Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:clustering· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

P. T. Spellman· 3 shared E. Demir· 2 shared G. B. Mills· 2 shared G. Thibault· 2 shared G. V. Thomas· 2 shared J. Eng· 2 shared Y. H. Chang· 2 shared A. Adey· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersCancer Biology

P. T. Spellman

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4 papers

Recent·Most cited

Multiplex imaging of localized prostate tumors reveals changes in mast cell type composition and spatial organization of AR-positive cells in the tumor microenvironment

C. Ak, Z. Sayar, G. Thibault, E. Burlingame, J. Eng, A. Chitsazan, A. Adey, C. Boniface, P. T. Spellman, G. V. Thomas, R. Kopp, E. Demir, Y. H. Chang, V. Stavrinides, S. E. Eksi

bioRxiv · Aug 18, 2023 · PreprintCancer Biology

An Omic and Multidimensional Spatial Atlas from Serial Biopsies of an Evolving Metastatic Breast Cancer

B. E. Johnson, A. L. Creason, J. M. Stommel, J. M. Keck, S. Parmar, C. B. Betts, A. Blucher, C. Boniface, E. Bucher, E. A. Burlingame, T. Camp, K. Chin, J. Eng, J. Estabrook, H. S. Feiler, , J. W. Gray

This paper presents an OMS Atlas from serial biopsies of a metastatic breast cancer patient, linking clinical data to multi-omic and spatial profiles to study therapy-associated heterogeneity and resistance mechanisms.

bioRxiv · Dec 3, 2020Cancer Biology

Multi-region exome sequencing of ovarian teratomas reveals 2N near-diploid genomes, paucity of somatic mutations, and extensive allelic imbalances shared across mature, immature, and disseminated components

M. B. Heskett, J. Z. Sanborn, C. Boniface, B. Goode, J. Chapman, K. Garg, J. T. Rabban, C. Zaloudek, S. C. Benz, P. T. Spellman, D. A. Solomon, R. J. Cho

This study uses multi-region exome sequencing to show ovarian immature teratomas have near-diploid genomes, extensive allelic imbalances, and clonal origins across different tumor components.

bioRxiv · Oct 28, 2019Cancer Biology

Targeting mitochondria in cancer therapy could provide a basis for the selective anti-cancer activity

D. Rozanov, A. Cheltsov, A. Nilsen, C. Boniface, J. Korkola, J. Gray, J. Tyner, C. E. Tognon, G. B. Mills, P. Spellman

The paper identifies key factors distinguishing non-toxic and toxic compounds targeting mitochondria in cancer therapy using SAR studies and a mathematical model.

bioRxiv · Oct 1, 2018Cancer Biology