Dysregulation of N-terminal acetylation causes cardiac arrhythmia and cardiomyopathy
D. Yoshinaga, R. Feng, M. Prondzynski, K. Shani, Y. Tharani, J. Milosh, D. Walker, K. Carreon, B. M. Boss, K. K. Parker, W. T. Pu, V. J. Bezzerides
This study identifies a mutation in NAA10 causing cardiac arrhythmia and cardiomyopathy by disrupting N-terminal acetylation, and shows potential therapeutic interventions.
bioRxiv · Jul 2, 2023Cell Biology