Author

K. K. Parker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

D. Walker· 2 shared K. Shani· 2 shared M. Prondzynski· 2 shared V. J. Bezzerides· 2 shared W. T. Pu· 2 shared Y. Tharani· 2 shared A. E. Cohen· 1 shared A. Hick· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

D. Walker

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Author profile →

4 papers

Recent·Most cited

Efficient and reproducible generation of human iPSC-derived cardiomyocytes using a stirred bioreactor

M. Prondzynski, R. H. Bortolin, P. Berkson, M. A. Trembley, K. Shani, M. E. Sweat, J. Mayourian, N. J. Anyanwu, A. M. Cordoves, Y. Tharani, J. Cotton, J. B. Milosh, D. Walker, Y. Zhang, F. Lu, , W. T. Pu

This paper describes a method to generate high-purity, scalable human iPSC-derived cardiomyocytes using a bioreactor, showing improved viability, function, and consistency compared to traditional methods.

bioRxiv · Feb 24, 2024 · PreprintCell Biology

Dysregulation of N-terminal acetylation causes cardiac arrhythmia and cardiomyopathy

D. Yoshinaga, R. Feng, M. Prondzynski, K. Shani, Y. Tharani, J. Milosh, D. Walker, K. Carreon, B. M. Boss, K. K. Parker, W. T. Pu, V. J. Bezzerides

This study identifies a mutation in NAA10 causing cardiac arrhythmia and cardiomyopathy by disrupting N-terminal acetylation, and shows potential therapeutic interventions.

bioRxiv · Jul 2, 2023Cell Biology

Structure-Function in Helical Cardiac Musculature Using Additive Textile Manufacturing

H. Chang, Q. Liu, J. F. Zimmerman, K. Y. Lee, Q. Jin, M. M. Peters, M. Rosnach, S. Choi, S. L. Kim, H. A. M. Ardona, L. A. MacQueen, C. O. Chantre, S. E. Motta, E. M. Cordoves, K. K. Parker

This study uses additive textile manufacturing to create helically aligned cardiac muscle models, showing improved mechanical function compared to circumferential models.

bioRxiv · Aug 18, 2021 · PreprintBioengineering

Prednisolone rescues Duchenne Muscular Dystrophy phenotypes in human pluripotent stem cells-derived skeletal muscle in vitro

Z. Al Tanoury, J. F. Zimmermann, J. Rao, D. Siero, H. McNamara, T. Cherrier, A. Hick, F. Bousson, C. Fugier, F. Marchiano, B. Habermann, J. Chal, A. P. Nesmith, S. Gapon, E. Wagner, , O. Pourquie

This study shows prednisolone rescues DMD phenotypes in iPSC-derived muscle cells, suggesting direct myofiber effects rather than just anti-inflammatory benefits.

bioRxiv · Oct 29, 2020Cell Biology