Quantifying glioblastoma drug response dynamics incorporating resistance and blood brain barrier penetrance from experimental data
S. C. Massey, J. C. Urcuyo, B. M. Marin, J. N. Sarkaria, K. R. Swanson
The paper develops a mathematical model to quantify glioblastoma drug response dynamics, finding that BBB permeability may slightly outweigh drug resistance in therapeutic efficacy.
bioRxiv · Oct 29, 2019Cancer Biology