CK1δ homeostasis by activity-dependent shuttling and degradation of orphan kinase
F. E. Serrano, D. Marzoll, B. Ruppert, A. C. R. Diernfellner, M. Brunner
The paper shows that CK1δ homeostasis is regulated by activity-dependent nuclear export and proteasomal degradation to balance its interactions and prevent excessive kinase activity.
bioRxiv · Feb 13, 2023 · PreprintBiochemistry