Comments on the recent crystal structure of TsaBDE complex of bacterial t6A biosynthesis system and its significance for understanding TC-AMP processing.
The paper corrects structural errors in the TsaBDE complex of Thermotoga maritima and shows that both active sites are occupied with TC-AMP, providing insights into t6A biosynthesis and tRNA binding.
bioRxiv · Feb 28, 2019 · PreprintBiophysics