ΔNp63-restricted viral mimicry response impedes cancer cell viability and remodels tumor microenvironment in esophageal squamous cell carcinoma
Valen Zhuoyou Yu, Shan Shan So, Bryan Chee-chad Lung, George Zhaozheng Hou, Carissa Wing-Yan Wong, Larry Ka-Yue Chow, Michael King Yung Chung, Yhi Wong, Claudia Lai-yin Wong, Desmond Kwan‐Kit Chan, Fion Siu‐Yin Chan, B. T.-t. Law, Kaiyan Xu, Zack Zhen Tan, Ka On Lam, , Maria Li Lung
This study identifies ΔNp63's role in restricting viral mimicry response in ESCC, reducing cell viability, and modulating tumor microenvironment immune cells.
Cancer Letters · May 31, 2024Peer-reviewedCancer Biology