Author

Valen Zhuoyou Yu

University of Hong KongORCID 0000-0002-3010-6012Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Anthony W.I. LoiD· 2 shared Bryan Chee-chad Lung· 2 shared Carissa Wing-Yan WongiD· 2 shared Dora Lai‐Wan KwongiD· 2 shared Josephine Mun Yee KoiD· 2 shared Maria Li LungiD· 2 shared Wei DaiiD· 2 shared Yhi WongiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersCancer Biology

Anthony W.I. LoORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 28, 2026

Disrupting Myeloid Persistence and Replenishment Enables Sustained Control of Esophageal Squamous Cell Carcinoma

Bryan Chee-chad Lung, Alvin Ka-Kiu Leung, Songran Liu…·Valen Zhuoyou Yu

The paper shows that combining CSF1R inhibition with low-dose decitabine suppresses both myeloid persistence and replenishment, leading to sustained control of ESCC in multiple models.

DOI 10.64898/2026.08.27.747541

humanmouse

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Cancer BiologyCancer LettersPeer-reviewedMay 31, 2024

ΔNp63-restricted viral mimicry response impedes cancer cell viability and remodels tumor microenvironment in esophageal squamous cell carcinoma

Valen Zhuoyou Yu, Shan Shan So, Bryan Chee-chad Lung…·Maria Li Lung

This study identifies ΔNp63's role in restricting viral mimicry response in ESCC, reducing cell viability, and modulating tumor microenvironment immune cells.

14 citations

humanbulk RNA-seq

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