Characterisation and structure determination of a llama-derived nanobody targeting the J-base binding protein 1
B. van Beusekom, T. Heidebrecht, A. Adamopoulos, A. Fish, E. Pardon, J. Steyaert, R. Joosten, A. Perrakis
The paper characterizes a llama-derived nanobody targeting JBP1, showing high affinity and solving its crystal structure to 1.64 Å resolution, with insights into CDR flexibility.
bioRxiv · Jun 7, 2018Biochemistry