Chromosomal arrangement of synthetic lethal gene pairs: repulsion or attraction?
S.-R. Hosseini, B. Wadie, E. Petsalaki
The paper analyzes synthetic lethal gene pairs in yeast and finds they are genomically closer in 2D and 3D space compared to random, contrasting with bacterial genomes where they are repelled.
bioRxiv · May 5, 2020 · PreprintEvolutionary Biology