Deciphering the molecular mechanisms of FET fusion oncoprotein-DNA hollow co-condensates
Linyu Zuo, Qirui Guo, Cheng Li, Kecheng Zhang, Yancao Chen, Baiyi Jiang, Zhixing Chen, Yufei Xia, Long Qian, Lei Zhang, Zhi Qi
This study investigates FUS-ERG fusion oncoprotein-DNA co-condensates, revealing nested asymmetric phase separation and their potential for DNA-based information manipulation.
Nature Communications · Nov 7, 2025Peer-reviewedBiophysics