Deep axonal proteomics of human iPSC-derived neurons by microfluidic separation and DIA-MS
Clemens M. Sauter, Zac Sandy, Milena Korneck, Vincent Albrecht, Melanie Kraft, Ramakrishnan Sivasubramanian, Barbora Kuttichova, Jared L. Sterneckert, Ludger J. Schöls, Alexandra K. Davies, Stefan Hauser
This paper reports the deepest human axonal proteome to date using microfluidic separation and DIA-MS on iPSC-derived neurons, identifying axon-enriched proteins and disease-related pathways.
bioRxiv · Jul 19, 2026 · PreprintNeuroscience