Reinforcement learning as an intermediate phenotype in psychosis? Deficits sensitive to illness stage but not associated with polygenic risk of schizophrenia in the general population
Marcella Montagnese, Franziska Knolle, Joost Haarsma, Juliet D. Griffin, Alexander L. Richards, Petra E. Vértes, Beatrix Kiddle, Paul Charles Fletcher, Peter Brian Jones, Michael John Owen, Peter Fonagy, Edward Thomas Bullmore, Raymond J. Dolan, Michael Moutoussis, Ian Michael Goodyer, Graham K. Murray
The paper assesses reinforcement learning deficits in psychosis risk groups and finds they are not linked to schizophrenia polygenic risk in the general population.
Schizophrenia Research · May 7, 2020Peer-reviewedNeuroscience