Petra E. Vértes

Inflections in adolescent cortical maturation signal psychopathology risk

The paper shows that differences in adolescent cortical maturation patterns predict psychiatric symptoms, with early maturing sensory regions linked to symptoms four years before their onset.

Human cortical networks trade communication efficiency for computational reliability.

The paper presents a game-theoretic model showing human cortical networks prioritize computational reliability over communication efficiency and wiring cost.

Genetic insights on the mechanisms of human cortical folding

This study identifies genetic maps of human sulcal complexity using rare and common variants, revealing new mechanistic pathways for cortical morphogenesis.

An entropic measure of diverse specialisation highlights multifunctional neurons in annotated connectomes

The paper introduces an entropic measure to identify multifunctional neurons by combining topological analysis with node metadata in connectomes of C. elegans and Drosophila.

A gene expression atlas of a juvenile nervous system

This study creates a gene expression atlas of C. elegans L1 neurons, identifying differentially expressed genes and regulatory networks involved in postembryonic neurogenesis and maturation.

Heterochronicity shapes brain network formation

This study introduces a heterochronous generative network model to better capture the spatial and temporal aspects of brain network development, improving model fit and identification of individual differences.

Homophilic wiring principles underpin neuronal network topology in vitro

This study identifies homophilic wiring as a principle governing neuronal network topology in vitro, outperforming traditional models in explaining connectivity patterns.

Molecular patterns of evolutionary changes throughout the whole nervous system of multiple nematode species

The paper analyzes whole-animal single-cell transcriptomes of nematodes to reveal stable neuronal identities but divergent signaling pathways across species.

A neuro-immune axis of transcriptomic dysregulation within the subgenual anterior cingulate cortex in schizophrenia

The paper identifies a schizophrenia-specific gene expression pattern in the subgenual anterior cingulate cortex using multivariate analysis, highlighting neuro-immune pathways and GWAS-implicated genes.

Genes with disrupted connectivity in the architecture of schizophrenia gene co-expression networks highlight atypical neuronal-glial interactions

The paper identifies genes with disrupted connectivity in schizophrenia gene co-expression networks, revealing atypical neuronal-glial interactions and synaptic transmission disturbances.

The brain cortical similarity network: Development and sensitivity to early life stress in a rat model

The paper uses MRI similarity network analysis to study how early life stress affects cortical network development in rats, finding altered inter-areal similarity in key brain regions.

Human adolescent brain similarity development is different for paralimbic versus neocortical zones

The paper examines how morphometric similarity in brain regions changes during adolescence, finding distinct developmental patterns in paralimbic versus neocortical areas.

A bipolar taxonomy of adult human brain sulcal morphology related to timing of fetalsulcation and trans-sulcal gene expression gradients

The paper constructs a sulcal phenotype network from MRI scans to identify two clusters of sulci related to developmental timing and gene expression gradients.

conn2res: A toolbox for connectome-based reservoir computing

conn2res is a Python toolbox that translates connectomes into artificial neural networks to study brain network computation.

Transcriptional Cartography Integrates Multiscale Biology of the Human Cortex

This paper integrates multiscale cortical biology by generating spatially dense gene expression maps from postmortem data, revealing transcriptional zones linked to microstructure and neuroimaging features.

System-wide mapping of neuropeptide-GPCR interactions in C. elegans

The paper reports a genome-wide map of neuropeptide-GPCR interactions in C. elegans, identifying 461 cognate peptide-GPCR pairs and uncovering their evolutionary conservation.

The neuropeptidergic connectome of C. elegans

The paper generates a draft connectome of neuropeptide signaling in C. elegans by integrating single-cell data with biochemical analysis.

Cortical gene expression architecture links healthy neurodevelopment to the imaging, transcriptomics, and genetics of autism and schizophrenia

The paper identifies new cortical gene expression components linked to neurodevelopment and finds associations with autism and schizophrenia across multiple data types.

Early adversity changes the economic conditions of structural brain network organisation

This paper uses computational modeling to show that early adversity increases stochasticity in the formation of structural brain networks in mice.

Sexually divergent development of depression-related brain networks during healthy human adolescence

The paper examines sex differences in brain network development during adolescence and links them to depression risk, finding divergent patterns in functional connectivity and gene expression.

An expanding manifold of transmodal regions characterizes adolescent reconfigurations of structural connectome organization

The paper uses manifold learning to analyze longitudinal structural connectome data, showing expansion in transmodal regions during adolescence and linking it to cognitive outcomes.

A generative network model of neurodevelopment

This paper introduces a computational framework to model brain network development, showing how genetic and topological factors shape neurodiverse outcomes through iterative wiring rules.

Reinforcement learning as an intermediate phenotype in psychosis? Deficits sensitive to illness stage but not associated with polygenic risk of schizophrenia in the general population

The paper assesses reinforcement learning deficits in psychosis risk groups and finds they are not linked to schizophrenia polygenic risk in the general population.

Multi-Subject Stochastic Blockmodels for Adaptive Analysis of Individual Differences in Human Brain Network Cluster Structure.

This paper introduces multi-subject stochastic blockmodels to analyze individual differences in brain network cluster structure, showing improved accuracy and robust statistical inference.

Schizotypy-related magnetization of cortex in healthy adolescence is co-located with expression of schizophrenia risk genes

The paper links schizotypy-related magnetization in adolescent cortex to schizophrenia risk genes using MRI and gene expression data.

Transcriptomic and Cellular Decoding of Regional Brain Vulnerability to Neurodevelopmental Disorders

The paper links genetic risks to spatial brain vulnerabilities in neurodevelopmental disorders using neuroimaging and gene expression data.

A moment of change: shifts in myeloarchitecture characterise adolescent development of cortical gradients

The paper investigates age-related changes in cortical myeloarchitecture during adolescence using longitudinal MRI data and identifies two distinct developmental processes.

Brain-behaviour modes of covariation in healthy and clinically depressed young people

The paper identifies two modes of brain-behavior covariation in adolescents and young adults using canonical correlation analysis, linking brain connectivity to psychometric, IQ, and demographic data.

Cortical patterning of abnormal morphometric similarity in psychosis is associated with brain expression of schizophrenia related genes

The paper links reduced cortical morphometric similarity in psychosis to the expression of schizophrenia-related genes in specific brain regions.

Conservative and disruptive modes of adolescent change in brain functional connectivity

The paper identifies two modes of brain functional connectivity change during adolescence: conservative and disruptive, with distinct patterns in primary and association cortex.